Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 13/20 | 0.36 |
| ▸ | QDPR | P09417 | 3/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20092262 | 0.83 | HDAC1 (0.39) | HDAC1HDAC2HDAC3TYK2QDPR | |
| SCHEMBL20093001 | 0.78 | TYK2 (0.38) | HDAC1HDAC2HDAC3TYK2 | |
| SCHEMBL2112353 | 0.77 | QDPR (0.49) | QDPR | |
| SCHEMBL14454641 | 0.77 | HDAC1 (0.42) | HDAC1HDAC2HDAC3QDPRWDR5 | |
| SCHEMBL30490281 | 0.76 | HDAC1 (0.40) | HDAC1HDAC2HDAC3TYK2WDR5 | |
| Hydrochloric Acid SCHEMBL4435866 | 0.76 | QDPR (0.47) | QDPR | |
| SCHEMBL20092137 | 0.74 | TYK2 (0.41) | TYK2 | |
| SCHEMBL20092749 | 0.73 | GLA (0.38) | — | |
| SCHEMBL1522466 | 0.71 | PTGES2 (0.48) | HDAC1HDAC2HDAC3 | |
| SCHEMBL5625544 | 0.70 | ACMSD (0.41) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |