Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 3/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20092262 | 0.81 | HDAC1 (0.39) | HDAC1HDAC2HDAC3WDR5L3MBTL1 | |
| SCHEMBL14454641 | 0.78 | HDAC1 (0.42) | HDAC1HDAC2HDAC3WDR5MAPT | |
| SCHEMBL25289702 | 0.76 | HDAC1 (0.36) | HDAC1HDAC2HDAC3WDR5TYK2 | |
| SCHEMBL20093001 | 0.75 | TYK2 (0.38) | HDAC1HDAC2HDAC3L3MBTL1TYK2 | |
| SCHEMBL29739838 | 0.74 | HDAC1 (0.37) | HDAC1HDAC2HDAC3WDR5LMNA | |
| SCHEMBL375209 | 0.73 | ALDH1A1 (0.42) | LMNAL3MBTL1SMN1; SMN2HTTPTGES2 | |
| SCHEMBL6130536 | 0.73 | CA12 (0.50) | LMNAL3MBTL1MAPTSMN1; SMN2HTT | |
| SCHEMBL1522466 | 0.72 | PTGES2 (0.48) | HDAC1HDAC2HDAC3LMNAHTT | |
| SCHEMBL2112353 | 0.72 | QDPR (0.49) | — | |
| SCHEMBL20092137 | 0.72 | TYK2 (0.41) | SMN1; SMN2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |