Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632115 | 0.98 | DNM1 (0.39) | DNM1TSHRTHRB | |
| SCHEMBL3629406 | 0.92 | DNM1 (0.31) | DNM1TSHR | |
| SCHEMBL3630886 | 0.81 | — | — | |
| SCHEMBL28922190 | 0.69 | TSHR (0.44) | DNM1TSHRTHRB | |
| SCHEMBL671910 | 0.67 | TSHR (0.41) | DNM1TSHRTHRB | |
| SCHEMBL28204325 | 0.67 | DNM1 (0.36) | DNM1TSHRTHRB | |
| SCHEMBL16281515 | 0.65 | TSHR (0.39) | DNM1TSHRTHRB | |
| Hexane SCHEMBL1972103 | 0.64 | TSHR (0.64) | DNM1TSHRTHRB | |
| Hexane SCHEMBL5792569 | 0.64 | TSHR (0.64) | DNM1TSHRTHRB | |
| SCHEMBL9277808 | 0.63 | TSHR (0.37) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389157-A1 | DRUG DELIVERY SYSTEM FOR USE IN THE TREATMENT OF VASCULAR AND VESSEL-RELATED PATHOLOGIES | Academisch Medisch Centrum (NL) | 2011-11-30 | — | — | EP | disclosed |
| US-8038960-B2 | Improves thermal efficiency by heating both inner and outer side surfaces of double cylindrical reforming chamber by combustion gas produced when burner is turned on, and in the reforming chamber, providing \"return pipes\" through which a produced reformed gas flows | IDEMITSU KOSAN CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010084199-A1 | DRUG DELIVERY SYSTEM FOR USE IN THE TREATMENT OF VASCULAR AND VESSEL-RELATED PATHOLOGIES | ACADEMISCH MEDISCH CENTRUM (NL) | 2010-07-29 | — | — | WO | disclosed |
| EP-2210590-A1 | Drug delivery system for use in the treatment of vascular and vessel-related pathologies | Academisch Medisch Centrum (NL) | 2010-07-28 | — | — | EP | disclosed |