Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529031 | 0.92 | DNM1 (0.35) | DNM1TSHR | |
| SCHEMBL3632115 | 0.90 | DNM1 (0.39) | DNM1LMNATSHR | |
| SCHEMBL3630886 | 0.83 | — | — | |
| SCHEMBL3630612 | 0.71 | — | — | |
| SCHEMBL2268334 | 0.69 | TSHR (0.35) | DNM1LMNATSHR | |
| SCHEMBL2103852 | 0.69 | TSHR (0.35) | DNM1LMNATSHR | |
| SCHEMBL2274484 | 0.67 | — | — | |
| SCHEMBL7768604 | 0.65 | TSHR (0.38) | LMNATSHR | |
| SCHEMBL2270140 | 0.65 | DNM1 (0.32) | DNM1LMNATSHR | |
| SCHEMBL3138105 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084199-A1 | DRUG DELIVERY SYSTEM FOR USE IN THE TREATMENT OF VASCULAR AND VESSEL-RELATED PATHOLOGIES | ACADEMISCH MEDISCH CENTRUM (NL) | 2010-07-29 | — | — | WO | disclosed |
| EP-2210590-A1 | Drug delivery system for use in the treatment of vascular and vessel-related pathologies | Academisch Medisch Centrum (NL) | 2010-07-28 | — | — | EP | disclosed |