SCHEMBL2529133

SCHEMBL2529133

ON=Cc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2529132 1.00
SCHEMBL2532900 0.90 CA1 (0.30)
SCHEMBL2532898 0.90 CA1 (0.30)
SCHEMBL1864386 0.86 TDP1 (0.35)
SCHEMBL1610490 0.82 NISCH (0.37)
SCHEMBL112195 0.80 CA1 (0.32)
SCHEMBL1609340 0.80 CYP3A4 (0.36)
SCHEMBL1864604 0.80 RECQL (0.34)
SCHEMBL1860377 0.80 PDK2 (0.32)
SCHEMBL2539855 0.80 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382196-B1 IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2015-08-12 EP disclosed
US-8722673-B2 Imine compounds for combating invertebrate pests BASF SE (DE) 2014-05-13 US disclosed
US-8633134-B2 Substituted amidine compounds for combating animal pests BASF SE (DE) 2014-01-21 US disclosed
EP-2382195-A1 SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2011-11-02 EP disclosed
EP-2382196-A2 IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2011-11-02 EP disclosed
US-20110263603-A1 Imine Compounds for Combating Invertebrate Pests BASF SE (DE) 2011-10-27 US disclosed
US-20110257011-A1 Substituted Amidine Compounds for Combating Animal Pests BASF SE (US) 2011-10-20 US disclosed
WO-2010072602-A1 SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2010-07-01 WO disclosed
WO-2010072781-A2 IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2010-07-01 WO disclosed