SCHEMBL112195

SCHEMBL112195

FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(c2ccc(Br)c(Cl)c2)=NO1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
RECQL P46063 1/20 0.32
PKM P14618 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112187 0.88 CA1 (0.33) CA1CA2RECQLPKMPDE3B
SCHEMBL13859320 0.88 CA1 (0.31) CA1CA2RECQLPKMPDE3B
SCHEMBL3068888 0.88 CA1 (0.31) CA1CA2RECQLPKMPDE3B
SCHEMBL13859317 0.88 CA1 (0.31) CA1CA2RECQLPKMPDE3B
SCHEMBL1611478 0.88 CA1 (0.32) CA1CA2RECQLPKM
SCHEMBL1610490 0.88 NISCH (0.37) CA1CA2RECQLPKM
SCHEMBL588568 0.86 RECQL (0.36) CA1CA2RECQLPKM
SCHEMBL14956592 0.86 CA1 (0.30) CA1CA2
SCHEMBL1612058 0.86 CA1 (0.33) CA1CA2RECQLPKM
SCHEMBL1304095 0.86 CA1 (0.33) CA1CA2RECQLPKMPDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382196-B1 IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2015-08-12 EP disclosed
US-9006447-B2 Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes BASF SE (DE) 2015-04-14 US disclosed
US-9006447-B2 Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes BASF SE (DE) 2015-04-14 US disclosed
EP-2424862-B1 PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS BASF SE (DE) 2014-10-08 EP disclosed
EP-2424862-B1 PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS BASF SE (DE) 2014-10-08 EP disclosed
US-8853410-B2 Process for preparing substituted isoxazoline compounds and their precursors BASF SE (DE) 2014-10-07 US disclosed
US-8853410-B2 Process for preparing substituted isoxazoline compounds and their precursors BASF SE (DE) 2014-10-07 US disclosed
US-8853410-B2 Process for preparing substituted isoxazoline compounds and their precursors BASF SE (DE) 2014-10-07 US disclosed
US-8722673-B2 Imine compounds for combating invertebrate pests BASF SE (DE) 2014-05-13 US disclosed
US-8633134-B2 Substituted amidine compounds for combating animal pests BASF SE (DE) 2014-01-21 US disclosed
US-20120059171-A1 Process for Preparing Substituted Isoxazoline Compounds and Their Precursors BASF SE (DE) 2012-03-08 US disclosed
EP-2424862-A1 PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS BASF SE (DE) 2012-03-07 EP disclosed
EP-2382195-A1 SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2011-11-02 EP disclosed
EP-2382196-A2 IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2011-11-02 EP disclosed
US-20110263603-A1 Imine Compounds for Combating Invertebrate Pests BASF SE (DE) 2011-10-27 US disclosed
US-20110257011-A1 Substituted Amidine Compounds for Combating Animal Pests BASF SE (US) 2011-10-20 US disclosed
WO-2010125130-A1 PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS BASF SE (DE) 2010-11-04 WO disclosed
WO-2010125130-A1 PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS BASF SE (DE) 2010-11-04 WO disclosed
WO-2010072602-A1 SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2010-07-01 WO disclosed
WO-2010072781-A2 IMINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2010-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263603-A1 Imine Compounds for Combating Invertebrate Pests INMT, PNMT, PIR CA1 4820/4885CA2 4729/4885RECQL 1433/4885
US-20110257011-A1 Substituted Amidine Compounds for Combating Animal Pests C5, C3AR1, C1S CA1 2108/4885CA2 2539/4885RECQL 48/4885
US-20120059171-A1 Process for Preparing Substituted Isoxazoline Compounds and Their Precursors CYP4X1, CYP3A7, CYP1B1 CA1 2963/4885CA2 3296/4885RECQL 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.