Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30491693 | 0.82 | MRGPRX4 (0.48) | TSHRSMN1; SMN2HPGDLMNAPTGES | |
| SCHEMBL1672182 | 0.82 | MRGPRX4 (0.48) | TSHRSMN1; SMN2HPGDLMNAPTGES | |
| SCHEMBL15540481 | 0.81 | LMNA (0.44) | TSHRSMN1; SMN2HPGDLMNAPTGES | |
| SCHEMBL16671517 | 0.81 | TSHR (0.47) | TSHRSMN1; SMN2HPGDLMNAPTGES | |
| SCHEMBL1671306 | 0.78 | CYP4F2 (0.56) | CYP4F2CYP4A11TSHRSMN1; SMN2HPGD | |
| SCHEMBL25291678 | 0.78 | MRGPRX4 (0.47) | TSHRSMN1; SMN2HPGDLMNAPTGES | |
| SCHEMBL15540600 | 0.76 | LMNA (0.40) | TSHRSMN1; SMN2HPGDLMNAPTGES | |
| SCHEMBL15540620 | 0.75 | HPGD (0.49) | TSHRSMN1; SMN2HPGDLMNAKDM4E | |
| SCHEMBL9932144 | 0.75 | PTGES (0.57) | CYP4F2CYP4A11TSHRSMN1; SMN2HPGD | |
| SCHEMBL15540381 | 0.73 | ALDH1A1 (0.45) | TSHRSMN1; SMN2HPGDLMNAPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023127883-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | 日本新薬株式会社 | 2023-07-06 | — | — | WO | disclosed |