Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242985 | 0.90 | CSNK2A1 (0.46) | TP53GAAALDH1A1TDP1MAPT | |
| SCHEMBL25282602 | 0.80 | TP53 (0.49) | TP53GAAALDH1A1TDP1MAPT | |
| SCHEMBL25290589 | 0.76 | ALDH1A1 (0.49) | TP53ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL25249722 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL25245871 | 0.75 | CSNK2A1 (0.44) | TP53ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL30251615 | 0.75 | TP53 (0.65) | TP53GAAALDH1A1TDP1MAPT | |
| SCHEMBL5093476 | 0.75 | TP53 (0.65) | TP53GAAALDH1A1TDP1MAPT | |
| SCHEMBL2116682 | 0.74 | TP53 (0.46) | TP53GAAALDH1A1TDP1MAPT | |
| SCHEMBL25285817 | 0.74 | TLR7 (0.48) | ALDH1A1TDP1MAPTKDM4EKMT2A | |
| SCHEMBL30487001 | 0.74 | DRD2 (0.48) | TP53GAAALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |