SCHEMBL25293264

SCHEMBL25293264

CC1(C)OB(c2cnn(CCCCCCCCCO)c2)OC1(C)C

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.58
LPL P06858 8/20 0.35
LIPG Q9Y5X9 8/20 0.35
PDK2 Q15119 1/20 0.34
GBA1 P04062 2/20 0.33
JAK2 O60674 1/20 0.32
JAK1 P23458 1/20 0.32
TYK2 P29597 1/20 0.32
JAK3 P52333 1/20 0.32
F11 P03951 1/20 0.32
DGAT1 O75907 1/20 0.30
IRAK4 Q9NWZ3 1/20 0.30
KLKB1 P03952 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25297920 1.00 FFAR1 (0.58) FFAR1LPLLIPGPDK2GBA1
SCHEMBL9281960 0.99 FFAR1 (0.59) FFAR1LPLLIPGPDK2GBA1
SCHEMBL1854359 0.94 FFAR1 (0.61) FFAR1LPLLIPGPDK2JAK2
SCHEMBL20759 0.88 FFAR1 (0.64) FFAR1LPLLIPGPDK2JAK2
SCHEMBL22748460 0.87 FFAR1 (0.56) FFAR1LPLLIPGGBA1
SCHEMBL23812347 0.87 FFAR1 (0.56) FFAR1LPLLIPGGBA1
SCHEMBL25248244 0.84 FFAR1 (0.53) FFAR1LIPGPDK2JAK2
SCHEMBL17247560 0.84 FFAR1 (0.58) FFAR1LPLLIPGF11IRAK4
SCHEMBL28398484 0.82 FFAR1 (0.57) FFAR1LPLLIPGF11IRAK4
SCHEMBL29582665 0.82 FFAR1 (0.61) FFAR1LPLLIPGF11DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-04-10 US disclosed
EP-4452978-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2024-10-30 EP disclosed
WO-2023115150-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 FFAR1 1395/4885LPL 1442/4885LIPG 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.