SCHEMBL25294095

SCHEMBL25294095

CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCCNC(N)=O)C(=O)NCOCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 2/20 0.49
▸ TLR2 O60603 2/20 0.45
▸ KMT2A Q03164 1/20 0.44
▸ PTPN1 P18031 5/20 0.44
▸ FURIN P09958 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31558981 0.91 PTPN1 (0.47) CASP3TLR2PTPN1
SCHEMBL18429578 0.90 KMT2A (0.52) CASP3TLR2KMT2APTPN1FURIN
SCHEMBL31047755 0.90 CASP3 (0.49) CASP3TLR2KMT2APTPN1FURIN
SCHEMBL35210479 0.90 CASP3 (0.49) CASP3TLR2KMT2APTPN1FURIN
SCHEMBL3193169 0.88 CASP3 (0.55) CASP3TLR2KMT2A
SCHEMBL13401540 0.88 CASP3 (0.55) CASP3TLR2KMT2A
SCHEMBL29702562 0.88 CASP3 (0.55) CASP3TLR2KMT2A
SCHEMBL13830553 0.88 CASP3 (0.55) CASP3TLR2KMT2A
SCHEMBL31045201 0.88 CASP3 (0.55) CASP3TLR2KMT2A
SCHEMBL29580018 0.88 CASP3 (0.55) CASP3TLR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124317-A2 Antibody Drug Conjugates BEONE MEDICINES I GMBH (CH) 2026-05-07 — — US disclosed
US-20250135026-A1 Antibody Drug Conjugates BEIGENE SWITZERLAND GMBH (CH) 2025-05-01 — — US disclosed
WO-2023125530-A1 ANTIBODY DRUG CONJUGATES BEIGENE, LTD. (KY) 2023-07-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124317-A2 Antibody Drug Conjugates SLC3A2, SLC7A1, SLC43A1 CASP3 3565/4885TLR2 926/4885KMT2A 2789/4885
US-20250135026-A1 Antibody Drug Conjugates CD22, FCGR2A, FCGR3B CASP3 4072/4885TLR2 3334/4885KMT2A 1834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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