Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530032 | 1.00 | ACHE (0.47) | ACHENAAACYP4F2CYP4A11EPHX1 | |
| SCHEMBL2532470 | 0.98 | ACHE (0.44) | ACHENAAACYP4F2CYP4A11 | |
| SCHEMBL16174327 | 0.98 | ACHE (0.44) | ACHENAAACYP4F2CYP4A11 | |
| SCHEMBL2527436 | 0.92 | ACHE (0.38) | ACHENAAA | |
| SCHEMBL17172479 | 0.89 | CYP4F2 (0.42) | ACHENAAACYP4F2CYP4A11 | |
| SCHEMBL12919784 | 0.88 | DGKA (0.51) | ACHENAAA | |
| SCHEMBL12112377 | 0.86 | DGKA (0.49) | ACHE | |
| SCHEMBL1626354 | 0.86 | NAAA (0.55) | ACHENAAAEPHX1 | |
| SCHEMBL8954907 | 0.86 | NAAA (0.55) | ACHENAAAEPHX1 | |
| SCHEMBL12757059 | 0.86 | NAAA (0.55) | ACHENAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |