Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MPL | P40238 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CCKAR | P32238 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24107627 | 0.89 | LMNA (0.58) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL24107525 | 0.88 | CYP1A1 (0.63) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL30292586 | 0.88 | CYP1A1 (0.63) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL24107512 | 0.87 | LMNA (0.58) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL24107671 | 0.87 | LMNA (0.55) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL24107586 | 0.86 | SMN1; SMN2 (0.51) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL24107450 | 0.86 | KMT2A (0.54) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL24107529 | 0.86 | MAPT (0.53) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL24107535 | 0.83 | MAPT (0.52) | LMNAKMT2ASMN1; SMN2MPLKDM4E | |
| SCHEMBL2753590 | 0.83 | LMNA (0.78) | LMNAKMT2ASMN1; SMN2MPLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212131-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212131-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | COL1A1, COL2A1, COL14A1 | LMNA 621/4885KMT2A 3819/4885SMN1; SMN2 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.