Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 7/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528744 | 0.90 | RIPK1 (0.39) | BACE1GLSMAOBPPARGPPARA | |
| SCHEMBL2527519 | 0.90 | ALOX5 (0.39) | BACE1FFAR1MAOB | |
| SCHEMBL2525775 | 0.90 | RIPK1 (0.39) | BACE1FFAR1MAOB | |
| SCHEMBL2527518 | 0.90 | PDGFRB (0.41) | BACE1L3MBTL1 | |
| SCHEMBL2529626 | 0.89 | KMT2A (0.40) | BACE1L3MBTL1PPARGPPARA | |
| SCHEMBL2528951 | 0.89 | L3MBTL1 (0.42) | L3MBTL1PPARGPPARA | |
| SCHEMBL2526471 | 0.88 | MEN1 (0.40) | L3MBTL1MAOB | |
| SCHEMBL2526481 | 0.88 | L3MBTL1 (0.38) | BACE1L3MBTL1PPARGPPARA | |
| SCHEMBL2533456 | 0.88 | CETP (0.43) | BACE1GLS | |
| SCHEMBL2530863 | 0.87 | AURKA (0.43) | L3MBTL1FFAR1GAAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | TAAR1 865/4885BACE1 1634/4885LTB4R 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.