Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376273 | 0.82 | ACHE (0.73) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28390756 | 0.78 | MAPT (0.82) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28390757 | 0.78 | MAPT (0.82) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL634357 | 0.77 | MAPT (1.00) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL634358 | 0.77 | MAPT (1.00) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL634385 | 0.77 | CHRNA7 (0.90) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL634386 | 0.77 | CHRNA7 (0.90) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25294508 | 0.77 | MAPT (0.59) | MAPTNPC1RAB9AMEN1KMT2A | |
| 4-Hydroxyisolonchocarpin SCHEMBL13535456 | 0.77 | XDH (0.81) | MAPTMEN1KMT2AMAPK1XDH | |
| SCHEMBL24728330 | 0.76 | TNFRSF1A (0.50) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |