Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.72 |
| ▸ | BACE1 | P56817 | 2/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | ODC1 | P11926 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960677 | 0.92 | XDH (0.80) | XDHPTPN1BACE1ACHEODC1 | |
| SCHEMBL13534948 | 0.85 | XDH (0.76) | XDHPTPN1BACE1ACHEODC1 | |
| SCHEMBL30383083 | 0.84 | PTPN1 (1.00) | XDHPTPN1BACE1ACHEODC1 | |
| SCHEMBL31297038 | 0.82 | XDH (0.57) | XDHPTPN1BACE1ACHEODC1 | |
| SCHEMBL31376263 | 0.78 | PTPN1 (1.00) | PTPN1BACE1ACHEODC1BCHE | |
| SCHEMBL19960679 | 0.78 | PTPN1 (1.00) | PTPN1BACE1ACHEODC1BCHE | |
| SCHEMBL25296934 | 0.77 | MAPT (0.61) | XDHPTPN1ACHEODC1CYP3A4 | |
| Demethylencecalin SCHEMBL31238098 | 0.76 | ALDH1A1 (1.00) | XDHPTPN1CYP3A4HPGDTDP1 | |
| Demethylencecalin SCHEMBL29903823 | 0.76 | ALDH1A1 (1.00) | XDHPTPN1CYP3A4HPGDTDP1 | |
| SCHEMBL29644899 | 0.75 | PTPN1 (0.61) | XDHPTPN1BACE1ACHEODC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) | 2018-03-15 | — | — | US | disclosed |
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) | 2018-03-15 | — | — | US | disclosed |
| WO-2010006184-A2 | SMALL-MOLECULE INHIBITORS OF HIF AND ANGIOGENESIS | EMORY UNIVERSITY (US) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | RAB35, GANC, GALE | XDH 227/4885PTPN1 4504/4885BACE1 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.