SCHEMBL25299001

SCHEMBL25299001

C=C(Cc1nc(C2(c3cc(Cl)cc(Cl)c3)CC2)no1)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ RAB9A P51151 1/20 0.31
▸ ALOX5AP P20292 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23578098 0.89 FFAR1 (0.35) MEN1HTTKMT2ARAB9ALMNA
SCHEMBL23578427 0.88 KMT2A (0.39) MEN1HTTKMT2ARAB9AALOX5AP
SCHEMBL23578206 0.87 MEN1 (0.32) MEN1HTTKMT2A
SCHEMBL23588170 0.87 RORC (0.32) MEN1HTTKMT2A
SCHEMBL23578426 0.87 MEN1 (0.32) MEN1HTTKMT2AALOX5AP
SCHEMBL25801965 0.84 MEN1 (0.32) MEN1HTTKMT2A
SCHEMBL23578437 0.84 KMT2A (0.42) MEN1HTTKMT2ARAB9AALOX5AP
SCHEMBL25805322 0.83 KMT2A (0.40) MEN1HTTKMT2AALOX5APLMNA
SCHEMBL23588358 0.82 MEN1 (0.34) MEN1HTTKMT2AALOX5APLMNA
SCHEMBL23578140 0.82 SLC6A3 (0.34) MEN1HTTKMT2AALOX5APLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066418-A Carboxy derivatives with anti-inflammatory properties 西特瑞治疗有限公司 2022-09-16 — — CN claimed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 — — US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 — — US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 — — US disclosed
CN-115066418-A Carboxy derivatives with anti-inflammatory properties 西特瑞治疗有限公司 2022-09-16 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 MEN1 4504/4885HTT 4546/4885KMT2A 3125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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