Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169235 | 0.86 | MAPK8 (0.54) | ADORA2AMAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL31746758 | 0.86 | MAPK8 (0.54) | ADORA2AMAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL13131265 | 0.76 | PTPN2 (0.59) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30578099 | 0.76 | MAPK8 (0.54) | ADORA2AMAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL120846 | 0.76 | MAPK8 (0.54) | ADORA2AMAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL8110850 | 0.76 | MAPK8 (0.64) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11495421 | 0.75 | RAD51 (0.65) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11417540 | 0.73 | MAPK8 (0.55) | ADORA2AMAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL14815430 | 0.73 | KDM4E (0.46) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11490588 | 0.72 | RAD51 (0.67) | ADORA2AMAPK8HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130701-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | 中山大学 | 2023-07-13 | — | — | WO | claimed |
| WO-2023130701-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | 中山大学 | 2023-07-13 | — | — | WO | disclosed |