SCHEMBL31746758

SCHEMBL31746758

Nc1nc2ccccc2n2ccnc12

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 7/20 0.54
HTR3E A5X5Y0 1/20 0.54
HTR3B O95264 1/20 0.54
HTR3A P46098 1/20 0.54
HTR3D Q70Z44 1/20 0.54
HTR3C Q8WXA8 1/20 0.54
ADORA2A P29274 9/20 0.49
ADORA1 P30542 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169235 1.00 MAPK8 (0.54) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL25299727 0.86 ADORA2A (0.53) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL30578099 0.79 MAPK8 (0.54) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL120846 0.79 MAPK8 (0.54) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL13131265 0.79 PTPN2 (0.59) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL8110850 0.79 MAPK8 (0.64) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL11495421 0.79 RAD51 (0.65) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL29138850 0.78 IKBKB (0.36) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL11417540 0.77 MAPK8 (0.55) MAPK8HTR3EHTR3BHTR3AHTR3D
SCHEMBL2947748 0.76 MAPK8 (0.53) MAPK8HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4667460-A1 MIR-124 INDUCER, AND PREPARATION METHOD THEREFOR AND USE THEREOF Nanjing Synnocare Pharmaceutical Technology Co., Ltd. (CN) 2025-12-24 EP disclosed