Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.54 |
| ▸ | HTR3B | O95264 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.54 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120846 | 1.00 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31377522 | 0.81 | MAPK8 (0.40) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8102963 | 0.80 | CUL4A (0.51) | MAPK8PTPN1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL169235 | 0.79 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31746758 | 0.79 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13131265 | 0.79 | PTPN2 (0.59) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11418210 | 0.79 | KDM4E (0.49) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24832295 | 0.78 | IKBKB (0.45) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3496046 | 0.78 | HTR3E (0.40) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30973203 | 0.78 | IKBKB (0.45) | MAPK8HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240110188-A1 | PREVENTION AND/OR TREATMENT OF INFLAMMATORY SKIN DISEASE | CONOPCO, INC., D/B/A UNILEVER | 2024-04-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240110188-A1 | PREVENTION AND/OR TREATMENT OF INFLAMMATORY SKIN DISEASE | CPA3, TPSAB1, CMA1 | MAPK8 2300/4885HTR3E 1613/4885HTR3B 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.