Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 7/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.50 |
| ▸ | RELA | Q04206 | 7/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25299087 | 0.88 | NFKB1 (0.48) | NFKB1NFKB2RELAMAPTPOLB | |
| SCHEMBL25437405 | 0.85 | NFKB1 (0.52) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL25301601 | 0.79 | MAPT (0.52) | NFKB1NFKB2RELAMAPTMAOB | |
| SCHEMBL25263882 | 0.75 | PDE4A (0.54) | NFKB1NFKB2RELAALDH1A1HPGD | |
| SCHEMBL12599532 | 0.75 | NFKB1 (0.50) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL17150170 | 0.74 | NFKB1 (0.66) | NFKB1NFKB2RELAMAPTPOLB | |
| SCHEMBL23728227 | 0.74 | NFKB1 (0.47) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL23728437 | 0.74 | NFKB1 (0.47) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL15620335 | 0.71 | NFKB1 (0.48) | NFKB1NFKB2RELAMAPTMAOB | |
| SCHEMBL15620334 | 0.71 | NFKB1 (0.48) | NFKB1NFKB2RELAMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |