SCHEMBL25302584

SCHEMBL25302584

CC(=O)NCCc1c[nH]c2ccc(F)c(F)c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MTNR1A P48039 13/20 0.61
▸ MTNR1B P49286 13/20 0.61
▸ NOTUM Q6P988 3/20 0.61
▸ NQO2 P16083 4/20 0.56
▸ CYP1A2 P05177 4/20 0.56
▸ BLM P54132 3/20 0.56
▸ MEN1 O00255 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ LMNA P02545 1/20 0.56
▸ PKM P14618 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ KDM4E B2RXH2 2/20 0.55
▸ ALDH1A1 P00352 2/20 0.55
▸ CYP3A4 P08684 2/20 0.55
▸ CYP2D6 P10635 2/20 0.55
▸ HPGD P15428 2/20 0.55
▸ MAPT P10636 1/20 0.55
▸ IDO1 P14902 1/20 0.55
▸ SPR P35270 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31543627 0.88 MTNR1A (0.60) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL31543656 0.88 MTNR1A (0.60) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL25382276 0.88 MTNR1A (0.60) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL26202196 0.84 MTNR1A (0.69) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL29799281 0.84 MTNR1A (0.55) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL25380213 0.84 MTNR1A (0.55) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL26202894 0.82 MTNR1A (0.53) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL13644764 0.80 CYP1A2 (0.60) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL25295069 0.78 MTNR1A (0.61) MTNR1AMTNR1BNOTUMNQO2CYP1A2
SCHEMBL29437233 0.78 MTNR1A (0.61) MTNR1AMTNR1BNOTUMNQO2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250057861-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2025-02-20 — — US disclosed
US-11998557-B2 Halogenated psilocybin derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2024-06-04 — — US disclosed
US-20230293558-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-09-21 — — US disclosed
US-20230293558-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-09-21 — — US disclosed
EP-4208445-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2023-07-12 — — EP disclosed
CN-116348106-A Halogenated nupharicin derivatives and methods of use 恩维瑞克生物科学加拿大公司 2023-06-27 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293558-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING CES2, MAOB, CNR1 MTNR1A 2036/4885MTNR1B 498/4885NOTUM 236/4885
US-11998557-B2 Halogenated psilocybin derivatives and methods of using CES2, MAOB, CNR1 MTNR1A 2036/4885MTNR1B 498/4885NOTUM 236/4885
US-20250057861-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING CES2, MAOB, CNR1 MTNR1A 2036/4885MTNR1B 498/4885NOTUM 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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