Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25295069 | 1.00 | MTNR1A (0.61) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL26202014 | 0.87 | MTNR1A (0.58) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL25383295 | 0.87 | MTNR1A (0.55) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL25381610 | 0.86 | MTNR1A (0.57) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL26202017 | 0.86 | MTNR1A (0.54) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL26202196 | 0.81 | MTNR1A (0.69) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL25302584 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL4488812 | 0.78 | MTNR1A (0.81) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 | |
| SCHEMBL31177155 | 0.78 | PTGS2 (0.66) | MTNR1AMTNR1BMEN1KMT2ARAB9A | |
| SCHEMBL30505588 | 0.78 | HTR2B (0.77) | MTNR1AMTNR1BNOTUMHTR2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348106-A | Halogenated nupharicin derivatives and methods of use | 恩维瑞克生物科学加拿大公司 | 2023-06-27 | — | — | CN | disclosed |