Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GSR | P00390 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL27617645 | 0.83 | KDM4E (0.37) | KDM4EMEN1KMT2ALMNAPOLB | |
| Diethanolamine SCHEMBL28560435 | 0.82 | GSR (0.38) | KDM4EMEN1KMT2ALMNAPOLB | |
| Ethylene Glycol SCHEMBL15658011 | 0.82 | ALDH1A1 (0.42) | KDM4EMEN1KMT2APOLBGGT1 | |
| Diethanolamine SCHEMBL11654955 | 0.77 | GSR (0.35) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| Ethylene Glycol SCHEMBL15658010 | 0.77 | ALDH1A1 (0.38) | KDM4EMEN1KMT2APOLBGGT1 | |
| Monoethanolamine SCHEMBL25299743 | 0.77 | TSHR (0.44) | KDM4EMEN1KMT2ALMNAGGT1 | |
| Diethanolamine SCHEMBL9588654 | 0.76 | ACHE (0.44) | KDM4EMEN1KMT2ALMNAPOLB | |
| Diethanolamine SCHEMBL9790976 | 0.76 | FFAR3 (0.44) | KDM4EMEN1KMT2ALMNAPOLB | |
| Diethanolamine SCHEMBL502768 | 0.76 | FFAR3 (0.44) | KDM4EMEN1KMT2ALMNAPOLB | |
| Diethanolamine SCHEMBL1832822 | 0.76 | KDM4E (0.39) | KDM4EMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250108339-A1 | ALKANOLAMINE-CONTAINING MEMBRANES AND METHODS OF MAKING AND USING THEREOF | UNITED STATES DEPARTMENT OFENERGY | 2025-04-03 | — | — | US | claimed |
| WO-2023141426-A1 | ALKANOLAMINE-CONTAINING MEMBRANES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2023-07-27 | — | — | WO | claimed |
| US-20250108339-A1 | ALKANOLAMINE-CONTAINING MEMBRANES AND METHODS OF MAKING AND USING THEREOF | UNITED STATES DEPARTMENT OFENERGY | 2025-04-03 | — | — | US | disclosed |
| WO-2023141426-A1 | ALKANOLAMINE-CONTAINING MEMBRANES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2023-07-27 | — | — | WO | disclosed |