Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL25307382 | 0.83 | KDM4E (0.36) | KDM4ELMNAMEN1KMT2APOLB | |
| Diethanolamine SCHEMBL502768 | 0.78 | FFAR3 (0.44) | KDM4ELMNAMEN1KMT2APOLB | |
| Diethanolamine SCHEMBL9790976 | 0.78 | FFAR3 (0.44) | KDM4ELMNAMEN1KMT2APOLB | |
| Diethanolamine SCHEMBL1832822 | 0.78 | KDM4E (0.39) | KDM4ELMNAMEN1KMT2APOLB | |
| Diethanolamine SCHEMBL1833343 | 0.78 | KDM4E (0.39) | KDM4ELMNAMEN1KMT2APOLB | |
| Trichloroacetic Acid SCHEMBL5874381 | 0.77 | ALDH1A1 (0.53) | KDM4ELMNAMEN1KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL356545 | 0.77 | CA3 (0.41) | KDM4ELMNAMEN1KMT2APOLB | |
| Diethanolamine SCHEMBL3630770 | 0.76 | FFAR3 (0.41) | KDM4ELMNAMEN1KMT2APOLB | |
| Acetic Acid SCHEMBL3929709 | 0.76 | FYN (0.41) | KDM4ELMNAMEN1KMT2APOLB | |
| Diethanolamine SCHEMBL11454426 | 0.76 | FFAR3 (0.41) | KDM4ELMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1643217-A | Slipping property imparting agent for clear coating and clear coating paper having the agent applied thereon | JUJO PAPER CO LTD (JP) | 2005-07-20 | — | — | CN | disclosed |