Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846066 | 0.95 | SIGMAR1 (0.47) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 | |
| SCHEMBL27916857 | 0.89 | SIGMAR1 (0.44) | SIGMAR1KCNH2HTR2AHRH1 | |
| SCHEMBL27309973 | 0.88 | SIGMAR1 (0.47) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 | |
| SCHEMBL28279553 | 0.88 | KCNH2 (0.51) | SIGMAR1KCNH2HTR2AHRH1ICMT | |
| Hydrochloric Acid SCHEMBL3635488 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL28704227 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL28705373 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 | |
| Bromide SCHEMBL28704238 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL28712149 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 | |
| Bromide SCHEMBL28705368 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2CSNK1EHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039625-B2 | Coronene charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-20090044863-A1 | CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2009-02-19 | — | — | US | disclosed |
| WO-2006093965-A2 | CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090044863-A1 | CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | SLC18A3, CORO1C, SLC18A1 | SIGMAR1 2736/4885KCNH2 995/4885CSNK1E 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.