SCHEMBL9846066

SCHEMBL9846066

CCCCCC(c1ccccc1)N(CCCC)CCCC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.47
HTR2A P28223 3/20 0.42
HRH1 P35367 2/20 0.42
KCNH2 Q12809 5/20 0.41
CSNK1E P49674 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
OPRM1 P35372 2/20 0.38
OPRD1 P41143 2/20 0.38
OPRK1 P41145 2/20 0.38
OPRL1 P41146 2/20 0.38
ALDH1A1 P00352 1/20 0.37
ASAH1 Q13510 1/20 0.37
ACER2 Q5QJU3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2530767 0.95 SIGMAR1 (0.50) SIGMAR1HTR2AHRH1KCNH2CSNK1E
SCHEMBL27916857 0.95 SIGMAR1 (0.44) SIGMAR1HTR2AHRH1KCNH2MEN1
SCHEMBL27309973 0.86 SIGMAR1 (0.47) SIGMAR1HTR2AHRH1KCNH2CSNK1E
SCHEMBL27872509 0.85 KCNH2 (0.44) SIGMAR1HTR2AHRH1KCNH2MEN1
Hydrochloric Acid SCHEMBL28712106 0.84 SIGMAR1 (0.46) SIGMAR1HTR2AHRH1KCNH2CSNK1E
Hydrochloric Acid SCHEMBL3635488 0.84 SIGMAR1 (0.46) SIGMAR1HTR2AHRH1KCNH2CSNK1E
Hydrochloric Acid SCHEMBL28710077 0.84 SIGMAR1 (0.46) SIGMAR1HTR2AHRH1KCNH2CSNK1E
Bromide SCHEMBL28705364 0.84 SIGMAR1 (0.46) SIGMAR1HTR2AHRH1KCNH2CSNK1E
Bromide SCHEMBL28694187 0.84 SIGMAR1 (0.46) SIGMAR1HTR2AHRH1KCNH2CSNK1E
Bromide SCHEMBL28709793 0.84 SIGMAR1 (0.46) SIGMAR1HTR2AHRH1KCNH2CSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424965-A1 Amine oxide process ETHYL CORPORATION (US) 1991-05-02 EP disclosed
US-4960934-A Amine oxide process ETHYL CORPORATION (US) 1990-10-02 US disclosed
EP-0307184-A2 Preparation of Amine Oxides ETHYL CORPORATION (US) 1989-03-15 EP disclosed