Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25304321 | 0.85 | PTGES (0.42) | SCN10A | |
| SCHEMBL25307004 | 0.84 | SCN10A (0.63) | SCN2ANPY5RSCN10A | |
| SCHEMBL30590468 | 0.83 | CACNA1H (0.51) | SCN2ATRPV1SSTR3NPY5RSCN10A | |
| SCHEMBL16210371 | 0.82 | MGLL (0.50) | SCN2AROCK2PRKCAGRK2KLK1 | |
| SCHEMBL25305748 | 0.79 | SCN2A (0.50) | SCN2ASSTR3SCN10A | |
| SCHEMBL25259225 | 0.78 | PDE2A (0.44) | SCN2ACOMT | |
| SCHEMBL5758675 | 0.77 | SCN2A (0.54) | SCN2ATRPV1SSTR3NPY5RSCN10A | |
| SCHEMBL25833757 | 0.76 | SCN2A (0.55) | SCN2ATRPV1SSTR3NPY5RSCN10A | |
| SCHEMBL25303515 | 0.76 | SCN2A (0.55) | SCN2ATRPV1SSTR3NPY5RSCN10A | |
| SCHEMBL5758137 | 0.75 | SCN2A (0.62) | SCN2ATRPV1SSTR3NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135057-A1 | BICYCLIC TRIAZINE DERIVATIVES FOR THE TREATMENT OF CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2023-07-20 | — | — | WO | disclosed |