Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NME4 | O00746 | 1/20 | 0.48 |
| ▸ | GCDH | Q92947 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25306854 | 0.91 | MAPT (0.57) | RAB9ANPC1SMN1; SMN2MAPTNME4 | |
| SCHEMBL25308935 | 0.86 | MAPT (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL25263437 | 0.86 | MAPT (0.52) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL25307575 | 0.83 | MAPT (0.54) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29033879 | 0.83 | MEN1 (0.57) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL25305249 | 0.77 | MAPT (0.65) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL25307234 | 0.77 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL12490766 | 0.75 | RAB9A (0.85) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL25309254 | 0.74 | MAPT (0.53) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11024162 | 0.72 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130540-A1 | PYRAZOL BENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州大学 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023130540-A1 | PYRAZOL BENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州大学 | 2023-07-13 | — | — | WO | disclosed |
| CN-114394934-A | Pyrazole benzamide compound and preparation method and application thereof | 苏州大学 | 2022-04-26 | — | — | CN | disclosed |