Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033877 | 0.84 | BCHE (0.65) | MEN1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL25308366 | 0.83 | RAB9A (0.55) | MEN1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL9137224 | 0.81 | KMT2A (0.73) | MEN1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL8442764 | 0.81 | KMT2A (0.73) | MEN1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL12490766 | 0.79 | RAB9A (0.85) | MEN1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL28301249 | 0.78 | BCHE (0.72) | MEN1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL16367722 | 0.77 | KMT2A (0.76) | MEN1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL20764247 | 0.76 | ACR (0.74) | MAPTACR | |
| SCHEMBL22978337 | 0.76 | TNIK (0.74) | DYRK1A | |
| SCHEMBL8572381 | 0.75 | KMT2A (0.83) | MEN1KMT2ARAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394934-B | Pyrazole benzamide compound as well as preparation method and application thereof | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |