Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528039 | 0.94 | CA1 (0.39) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL2529013 | 0.92 | NAAA (0.41) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL2533185 | 0.92 | NAAA (0.41) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL2528827 | 0.90 | DGKA (0.42) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL14308492 | 0.90 | CA1 (0.44) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL25886908 | 0.90 | CA1 (0.44) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL2531970 | 0.88 | CA1 (0.43) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL7591037 | 0.88 | CA1 (0.43) | CA1DGKAADRA2AADRA1ACYP19A1 | |
| SCHEMBL2530041 | 0.85 | DGKA (0.41) | DGKAADRA2AADRA1ACYP19A1MAPT | |
| SCHEMBL25888671 | 0.85 | CA1 (0.38) | CA1DGKAADRA2AADRA1ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |