Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529013 | 1.00 | NAAA (0.41) | NAAADGKAHTR2CCA1PRSS1 | |
| SCHEMBL2528039 | 0.98 | CA1 (0.39) | NAAADGKAHTR2CCA1PRSS1 | |
| SCHEMBL2530841 | 0.92 | CA1 (0.40) | NAAADGKAHTR2CCA1MAPT | |
| SCHEMBL2527693 | 0.91 | DGKA (0.44) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL2525934 | 0.91 | DGKA (0.44) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14308492 | 0.90 | CA1 (0.44) | NAAADGKAHTR2CCA1PRSS1 | |
| SCHEMBL2530041 | 0.89 | DGKA (0.41) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL28455937 | 0.89 | NAAA (0.44) | NAAADGKAHTR2CCA1PRSS1 | |
| SCHEMBL28460112 | 0.89 | NAAA (0.44) | NAAADGKAHTR2CCA1PRSS1 | |
| SCHEMBL28446535 | 0.89 | NAAA (0.44) | NAAADGKAHTR2CCA1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |