Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248123 | 0.85 | ALDH1A1 (0.41) | JMJD6DGAT1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL19926085 | 0.82 | KMT2A (0.49) | DGAT1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL18074464 | 0.79 | SMN1; SMN2 (0.39) | DGAT1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL24719220 | 0.79 | SMN1; SMN2 (0.51) | DGAT1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL15351865 | 0.78 | NPC1 (0.42) | DGAT1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL25312179 | 0.71 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL8543719 | 0.71 | ESRRA (0.38) | ALDH1A1KMT2AKDM4ETP53HPGD | |
| SCHEMBL29601443 | 0.70 | KMT2A (0.39) | DGAT1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL31308722 | 0.70 | DGAT1 (0.35) | DGAT1NPC1 | |
| SCHEMBL5246866 | 0.69 | NPC1 (0.33) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134765-A1 | FIVE-MEMBERED-RING-CONTAINING DERIVATIVES, PREPARATION METHOD THEREFOR, AND USES THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |