Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102820 | 0.89 | KMT2A (0.57) | KMT2AKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL28203274 | 0.86 | LMNA (0.45) | KMT2AKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL25866702 | 0.83 | L3MBTL1 (0.53) | KMT2AKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL29651318 | 0.83 | L3MBTL1 (0.53) | KMT2AKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL2184960 | 0.82 | NR4A2 (0.55) | KMT2AKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL13203774 | 0.82 | NR4A2 (0.55) | KMT2AKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL29433116 | 0.82 | KDM4E (0.43) | KMT2AKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL27855164 | 0.79 | KDM4E (0.41) | KMT2AKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL369096 | 0.79 | KMT2A (0.52) | KMT2AKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL14678552 | 0.74 | ALDH1A1 (0.45) | KMT2AKDM4EALDH1A1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134608-A1 | FUSED RING COMPOUNDS SERVING AS HPK1 INHIBITORS | 微境生物医药科技(上海)有限公司 | 2023-07-20 | — | — | WO | disclosed |