Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474219 | 1.00 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL30979300 | 0.86 | L3MBTL1 (0.39) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL25307791 | 0.84 | KMT2A (0.39) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL25380351 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTCYP1A2 | |
| SCHEMBL28537725 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL28529013 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL18304994 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL29215523 | 0.76 | PDGFRB (0.41) | ALDH1A1KMT2AMEN1MAPTCYP1A2 | |
| SCHEMBL31474310 | 0.76 | KMT2A (0.47) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL29215568 | 0.76 | KMT2A (0.47) | ALDH1A1KMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466269-A1 | PARP1 INHIBITORS AND USES THEREOF | Xinthera, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| US-20240368162-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2024-11-07 | — | — | US | disclosed |
| CN-118076597-A | Azaquinolinone derivative, preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-11939329-B2 | PARP1 inhibitors and uses thereof | XINTHERA, INC. (US) | 2024-03-26 | — | — | US | disclosed |
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2023-07-27 | — | — | US | disclosed |
| WO-2023141290-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939329-B2 | PARP1 inhibitors and uses thereof | PARP1, PARP11, PARP12 | ALDH1A1 1913/4885KMT2A 944/4885MEN1 3207/4885 |
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | PARP1, PARP11, PARP12 | ALDH1A1 1913/4885KMT2A 944/4885MEN1 3207/4885 |
| US-20240368162-A1 | PARP1 INHIBITORS AND USES THEREOF | PARP1, PARP11, PARP12 | ALDH1A1 1913/4885KMT2A 944/4885MEN1 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.