Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
| ▸ | VNN1 | O95497 | 10/20 | 0.45 |
| ▸ | GRM5 | P41594 | 5/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30460433 | 1.00 | GSK3B (0.51) | GSK3BVNN1GRM5BRAFMAPK14 | |
| SCHEMBL30460446 | 0.85 | GSK3B (0.51) | GSK3BVNN1GRM5BRAF | |
| SCHEMBL25310344 | 0.85 | GSK3B (0.51) | GSK3BVNN1GRM5BRAF | |
| SCHEMBL25261381 | 0.85 | GSK3B (0.51) | GSK3BVNN1GRM5BRAF | |
| SCHEMBL30460403 | 0.85 | GSK3B (0.51) | GSK3BVNN1GRM5BRAF | |
| SCHEMBL1847397 | 0.79 | GSK3B (0.59) | GSK3BVNN1GRM5 | |
| SCHEMBL30460451 | 0.79 | GSK3B (0.59) | GSK3BVNN1GRM5 | |
| SCHEMBL3074382 | 0.78 | PLOD2 (0.53) | — | |
| SCHEMBL16060791 | 0.75 | KDM4E (0.48) | MAPK14 | |
| SCHEMBL25310003 | 0.75 | GSK3B (0.51) | GSK3BVNN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101013-A1 | FUNCTIONALIZED AMINOTHIAZOLES | LEADXPRO AG (CH) | 2025-03-27 | — | — | US | disclosed |
| EP-4466267-A1 | FUNCTIONALIZED AMINOTHIAZOLES | LeadXpro AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139132-A1 | FUNCTIONALIZED AMINOTHIAZOLES | LEADXPRO AG (CH) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023139132-A1 | FUNCTIONALIZED AMINOTHIAZOLES | LEADXPRO AG (CH) | 2023-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101013-A1 | FUNCTIONALIZED AMINOTHIAZOLES | ADORA2B, RB1, ADORA3 | GSK3B 3066/4885VNN1 4091/4885GRM5 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.