Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 18/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25314281 | 0.91 | ALDH1A1 (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL30989721 | 0.91 | ALDH1A1 (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL31081542 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25314138 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25314770 | 0.88 | PIK3C2A (0.37) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25318005 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25885744 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25885544 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL25887409 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA | |
| SCHEMBL30989716 | 0.83 | PIK3C2A (0.35) | ALDH1A1KCNH2PIK3C2APIK3C2BPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103464-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2026-04-16 | — | — | US | disclosed |
| US-12435083-B2 | Cyclopropyl-(hetero)aryl-substituted ethylsulphonyl-pyridine derivatives | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-10-07 | — | — | US | disclosed |
| US-20240327414-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL- SULFONE / SULFOXIMINE-PYRIDINE N-OXIDE DERIVATIVES | Boehringer Ingelheim Animal Health USA Inc. | 2024-10-03 | — | — | US | disclosed |
| WO-2024175558-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFONE/SULFOXIMINE-PYRIDINE N-OXIDE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | CYCS, CYP2E1, AHR | ALDH1A1 637/4885KCNH2 1388/4885PIK3C2A 3437/4885 |
| US-20240327414-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL- SULFONE / SULFOXIMINE-PYRIDINE N-OXIDE DERIVATIVES | SQOR, PNPO, STS | ALDH1A1 1476/4885KCNH2 3164/4885PIK3C2A 3900/4885 |
| US-12435083-B2 | Cyclopropyl-(hetero)aryl-substituted ethylsulphonyl-pyridine derivatives | CYCS, CYP2E1, CYP1A1 | ALDH1A1 512/4885KCNH2 1417/4885PIK3C2A 3512/4885 |
| US-20260103464-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | CBR3, CYCS, CBR1 | ALDH1A1 2267/4885KCNH2 508/4885PIK3C2A 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.