SCHEMBL25313489

SCHEMBL25313489

NC(=O)C1C(=O)N(c2ccc(F)c(F)c2F)CC1c1cccc(C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RPS6KB1 P23443 1/20 0.38
AKT1 P31749 1/20 0.38
HTR2B P41595 2/20 0.37
GUSB P08236 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
CETP P11597 1/20 0.36
HTR7 P34969 1/20 0.36
GPR52 Q9Y2T5 1/20 0.35
FPR1 P21462 4/20 0.35
FPR2 P25090 4/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.34
RECQL P46063 1/20 0.34
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
DRD3 P35462 1/20 0.33
AADAT Q8N5Z0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25317840 0.93 HTR2B (0.38) RPS6KB1AKT1HTR2BGUSBHTR2A
SCHEMBL22493136 0.90 RPS6KB1 (0.41) RPS6KB1AKT1HTR2BGUSBHTR2A
SCHEMBL21638330 0.88 ALDH1A1 (0.40) RPS6KB1AKT1HTR2BGUSBHTR2A
SCHEMBL25319499 0.88 ALDH1A1 (0.40) RPS6KB1AKT1HTR2BGUSBHTR2A
SCHEMBL25317498 0.87 RPS6KB1 (0.35) RPS6KB1HTR2CFPR1FPR2AADAT
SCHEMBL22493137 0.83 RPS6KB1 (0.39) RPS6KB1AKT1HTR2BHTR2AHTR2C
SCHEMBL22493132 0.83 RPS6KB1 (0.39) RPS6KB1AKT1HTR2BHTR2AHTR2C
SCHEMBL25315680 0.82 SIRT2 (0.38) RPS6KB1FPR1FPR2KMT2AAADAT
SCHEMBL25313673 0.80 KDM1A (0.36) HTR2BHTR2AHTR2CAADAT
SCHEMBL25224614 0.78 HTR2B (0.43) RPS6KB1AKT1HTR2BGUSBHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3890487-B1 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2024-06-12 EP claimed
EP-3923724-B1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-26 EP claimed