Sugi Predict

Sugi Predict / Compounds / SCHEMBL25313709

SCHEMBL25313709

SCHEMBL25313709

O=S(=O)(c1ccc(OC(F)F)cc1)N1C2CCC1CC(N1CC3CCC(C3)C1)C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGDR2 Q9Y5Y4 2/20 0.40
▸ DHCR7 Q9UBM7 1/20 0.40
▸ ELOVL6 Q9H5J4 4/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ HSD11B1 P28845 4/20 0.38
▸ KDM2B Q8NHM5 1/20 0.38
▸ ESR1 P03372 1/20 0.38
▸ LMNA P02545 2/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ PSEN1 P49768 1/20 0.36
▸ PSEN2 P49810 1/20 0.36
▸ APH1B Q8WW43 1/20 0.36
▸ NCSTN Q92542 1/20 0.36
▸ APH1A Q96BI3 1/20 0.36
▸ PSENEN Q9NZ42 1/20 0.36
▸ DRD2 P14416 1/20 0.35
▸ ADRA1D P25100 1/20 0.35
▸ ADRA1A P35348 1/20 0.35
▸ ADRA1B P35368 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25891914 0.96 PTGDR2 (0.41) PTGDR2DHCR7ELOVL6ALDH1A1HSD11B1
SCHEMBL25429083 0.82 DHCR7 (0.61) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25315410 0.82 DHCR7 (0.61) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25315405 0.82 DHCR7 (0.61) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25315710 0.82 DHCR7 (0.61) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25429080 0.82 DHCR7 (0.61) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25316374 0.82 DHCR7 (0.61) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25891909 0.81 HSD11B1 (0.41) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25315976 0.81 ALDH1A1 (0.43) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B
SCHEMBL25317874 0.81 ALDH1A1 (0.43) PTGDR2DHCR7ALDH1A1HSD11B1KDM2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-22 — — US claimed
EP-4469155-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2024-12-04 — — EP claimed
WO-2023141323-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-07-27 — — WO claimed
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-22 — — US disclosed
EP-4469155-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2024-12-04 — — EP disclosed
WO-2023141323-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-07-27 — — WO disclosed
WO-2023141323-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-07-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP PTGDR2 2620/4885DHCR7 2873/4885ELOVL6 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.