Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CLK1 | P49759 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25313843 | 0.94 | CYP4F2 (0.45) | CYP4F2CYP4A11RAB9ACLK1NPC1 | |
| SCHEMBL25314240 | 0.94 | CYP4F2 (0.45) | CYP4F2CYP4A11RAB9ACLK1NPC1 | |
| SCHEMBL25314885 | 0.87 | CYP4F2 (0.43) | CYP4F2CYP4A11RAB9ACLK1NPC1 | |
| SCHEMBL25894011 | 0.85 | RAB9A (0.44) | RAB9ANPC1CHRM5CHRM1CHRM4 | |
| SCHEMBL25316195 | 0.83 | ALDH1A1 (0.51) | RAB9ANPC1KMT2APOLB | |
| SCHEMBL338133 | 0.80 | CYP4F2 (0.51) | CYP4F2CYP4A11RAB9ACLK1NPC1 | |
| SCHEMBL25894009 | 0.78 | RAB9A (0.42) | RAB9ANPC1CHRM5CHRM1CHRM4 | |
| SCHEMBL25894017 | 0.78 | RAB9A (0.42) | RAB9ANPC1CHRM5CHRM1CHRM4 | |
| SCHEMBL25894268 | 0.77 | CYP4F2 (0.46) | CYP4F2CYP4A11RAB9ACLK1NPC1 | |
| SCHEMBL25312682 | 0.76 | ALDH1A1 (0.49) | RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-07-27 | — | — | US | claimed |
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-07-27 | — | — | US | disclosed |
| EP-4161493-A1 | AZIRINE CONTAINING COMPOUNDS AS ANTI-ANGIOGENESIS AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2023-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | FLT1, PGF, KDR | CYP4F2 666/4885CYP4A11 602/4885RAB9A 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.