Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038666 | 0.86 | KMT2A (0.33) | L3MBTL1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL5366517 | 0.86 | KMT2A (0.33) | L3MBTL1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL1577617 | 0.77 | L3MBTL1 (0.42) | L3MBTL1ADORA1POLBSMN1; SMN2NPC1 | |
| SCHEMBL1661669 | 0.76 | KMT2A (0.47) | L3MBTL1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL267725 | 0.75 | L3MBTL1 (0.44) | L3MBTL1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL3326127 | 0.74 | L3MBTL1 (0.43) | L3MBTL1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL1047479 | 0.74 | L3MBTL1 (0.43) | L3MBTL1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL19691913 | 0.74 | CTSA (0.39) | L3MBTL1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL5366980 | 0.73 | KMT2A (0.40) | L3MBTL1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5374156 | 0.73 | L3MBTL1 (0.42) | L3MBTL1MAPTMEN1KMT2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023127814-A1 | SUBSTITUTED QUINOLINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2023-07-06 | — | — | WO | disclosed |