Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661669 | 0.85 | KMT2A (0.47) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL267717 | 0.83 | L3MBTL1 (0.44) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL1047479 | 0.82 | L3MBTL1 (0.43) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL3326127 | 0.82 | L3MBTL1 (0.43) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL5374156 | 0.81 | L3MBTL1 (0.42) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL12780025 | 0.81 | L3MBTL1 (0.42) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL14999156 | 0.80 | L3MBTL1 (0.44) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL25386662 | 0.80 | L3MBTL1 (0.41) | L3MBTL1HTTMEN1KMT2AADORA1 | |
| SCHEMBL30884722 | 0.80 | PARP2 (0.45) | L3MBTL1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL247107 | 0.80 | L3MBTL1 (0.41) | L3MBTL1HTTMEN1KMT2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134007-B2 | Pyridine derivatives | PFIZER INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090048306-A1 | PYRIDINE DERIVATIVES | PFIZER, INC. (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048306-A1 | PYRIDINE DERIVATIVES | SDHA, P2RX4, P2RX3 | L3MBTL1 4806/4885HTT 3191/4885MEN1 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.