Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375594 | 0.85 | KMT2A (0.34) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27635422 | 0.79 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17980699 | 0.78 | L3MBTL1 (0.54) | CTSAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5363322 | 0.76 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1661669 | 0.74 | KMT2A (0.47) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5383471 | 0.74 | LMNA (0.40) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL25315958 | 0.74 | L3MBTL1 (0.37) | CTSAL3MBTL1ALDH1A1MAPTMEN1 | |
| SCHEMBL267725 | 0.73 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3326127 | 0.72 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1047479 | 0.72 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468970-A1 | NEW ANTIBACTERIAL COMPOUNDS | Aziende Chimiche Riunite Angelini Francesco A.C.R. (IT) | 2019-04-17 | — | — | EP | disclosed |
| EP-3468975-A1 | NEW ANTIBACTERIAL COMPOUNDS | Aziende Chimiche Riunite Angelini Francesco A.C.R. (IT) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017211760-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-12-14 | — | — | WO | disclosed |
| WO-2017211759-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-12-14 | — | — | WO | disclosed |