Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317194 | 0.85 | RAB9A (0.56) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL25317747 | 0.84 | RAB9A (0.82) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL9693079 | 0.82 | RAB9A (0.60) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL9843023 | 0.82 | RAB9A (0.60) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL9690532 | 0.81 | RAB9A (0.70) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| Bromide SCHEMBL9692623 | 0.81 | RAB9A (0.59) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL25318784 | 0.80 | RAB9A (0.56) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL9690499 | 0.79 | RAB9A (0.83) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL25321130 | 0.78 | RAB9A (0.62) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL9692749 | 0.78 | CYP2D6 (0.65) | RAB9ASMN1; SMN2TP53KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081253-A | IMIDAZO(4,5-C)PYRIDINES AS ANTIOSTEOPOROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0434405-A1 | Imidazo[4,5-c]pyridines as antiosteoporotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-26 | — | — | EP | disclosed |