Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 2/20 | 0.47 |
| ▸ | SKP1 | P63208 | 2/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 6/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475514 | 1.00 | DDB1 (0.47) | DDB1CRBNCKS1BSKP1SKP2 | |
| SCHEMBL28406959 | 0.90 | DDB1 (0.50) | DDB1CRBNCKS1BSKP1SKP2 | |
| SCHEMBL25322835 | 0.83 | GPR119 (0.48) | CKS1BSKP1SKP2GPR119MAP4K4 | |
| SCHEMBL31314534 | 0.82 | NAMPT (0.45) | CKS1BSKP1SKP2MAP4K4JAK2 | |
| SCHEMBL12453384 | 0.82 | NAMPT (0.45) | CKS1BSKP1SKP2MAP4K4JAK2 | |
| SCHEMBL29980884 | 0.82 | OPRD1 (0.42) | CKS1BSKP1SKP2GPR119OPRD1 | |
| SCHEMBL12489219 | 0.82 | OPRD1 (0.42) | CKS1BSKP1SKP2GPR119OPRD1 | |
| SCHEMBL19491057 | 0.82 | OPRD1 (0.42) | CKS1BSKP1SKP2GPR119OPRD1 | |
| SCHEMBL2884922 | 0.82 | JAK2 (0.46) | CKS1BSKP1SKP2GPR119JAK2 | |
| SCHEMBL29475511 | 0.82 | JAK2 (0.46) | CKS1BSKP1SKP2GPR119JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759563-B | Preparation method of 4- (6-substituted aminopyridine-3-yl) piperidine-1-tert-butyl formate | 上海再启生物技术有限公司 | 2020-06-02 | — | — | CN | claimed |
| US-20240043395-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | NEUROPORE THERAPIES, INC. | 2024-02-08 | — | — | US | disclosed |
| EP-4217342-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | Neuropore Therapies, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116507607-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-107759563-B | Preparation method of 4- (6-substituted aminopyridine-3-yl) piperidine-1-tert-butyl formate | 上海再启生物技术有限公司 | 2020-06-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043395-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | TLR3, TLR6, TLR4 | DDB1 2027/4885CRBN 1677/4885CKS1B 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.