Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513396 | 0.96 | SCD5 (0.51) | SCD5RIPK1ROCK2KMT2AHSD11B1 | |
| SCHEMBL22498217 | 0.96 | SCD5 (0.51) | SCD5RIPK1ROCK2KMT2AHSD11B1 | |
| SCHEMBL25322785 | 0.87 | RIPK1 (0.45) | SCD5RIPK1ROCK2BACE1KMT2A | |
| SCHEMBL28097481 | 0.84 | HSP90AA1 (0.53) | RIPK1ROCK2HSD11B1PARP14PARP10 | |
| SCHEMBL27574934 | 0.83 | RIPK1 (0.62) | SCD5RIPK1BACE1HSD11B1PARP14 | |
| SCHEMBL216202 | 0.83 | RIPK1 (0.62) | SCD5RIPK1BACE1HSD11B1PARP14 | |
| SCHEMBL27574946 | 0.83 | RIPK1 (0.62) | SCD5RIPK1BACE1HSD11B1PARP14 | |
| SCHEMBL27341297 | 0.83 | PRMT5 (0.49) | SCD5RIPK1ROCK2HSD11B1 | |
| SCHEMBL6246105 | 0.83 | RIPK1 (0.66) | SCD5RIPK1HSD11B1PARP14PARP10 | |
| SCHEMBL31578455 | 0.82 | USP30 (0.50) | SCD5RIPK1ROCK2KMT2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |