SCHEMBL2531983

SCHEMBL2531983

O=C(C#CC(=O)OC1CCCCC1)OC1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.48
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
CYP2C19 P33261 1/20 0.42
NAAA Q02083 2/20 0.41
HTT P42858 1/20 0.40
STS P08842 4/20 0.39
CYP19A1 P11511 3/20 0.38
MMP1 P03956 1/20 0.37
MMP9 P14780 1/20 0.37
MMP12 P39900 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
FABP7 O15540 1/20 0.36
FABP5 Q01469 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2528803 0.97 EPHX1 (0.45) EPHX1CA1CA2CA12CA9
SCHEMBL25333252 0.91 EPHX1 (0.42) EPHX1CA1CA2CA12CA9
SCHEMBL8411729 0.87 EPHX1 (0.42) EPHX1CA1CA2CA12CA9
SCHEMBL733037 0.83 EPHX1 (0.47) EPHX1CA1CA2CA12CA9
SCHEMBL31339503 0.81 EPHX1 (0.45) EPHX1CA1CA2CA12CA9
SCHEMBL27981763 0.81 EPHX1 (0.45) EPHX1CA1CA2CA12CA9
SCHEMBL6207813 0.81 EPHX1 (0.45) EPHX1CA1CA2CA12CA9
SCHEMBL11473389 0.81 EPHX1 (0.45) EPHX1CA1CA2CA12CA9
SCHEMBL31339498 0.81 EPHX1 (0.45) EPHX1CA1CA2CA12CA9
SCHEMBL27567894 0.79 NAAA (0.46) EPHX1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112768773-A Electrolyte and lithium ion battery 蜂巢能源科技有限公司 2021-05-07 CN claimed
US-12466907-B2 Acrylic rubber composition and rubber crosslinked product ZEON CORPORATION (JP) 2025-11-11 US disclosed
US-12162969-B2 Acrylic rubber, acrylic rubber composition, crosslinked acrylic rubber, seal material, and hose material ZEON CORPORATION (JP) 2024-12-10 US disclosed
EP-3778661-B1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION, CROSSLINKED ACRYLIC RUBBER, SEAL MATERIAL, AND HOSE MATERIAL ZEON CORP (JP) 2024-01-10 EP disclosed
CN-114080401-B Acrylic rubber, acrylic rubber composition, and crosslinked rubber 日本瑞翁株式会社 2023-05-16 CN disclosed
CN-111918883-B Method for producing acrylic rubber, method for producing acrylic rubber composition, and biaxial extrusion dryer for acrylic rubber 日本瑞翁株式会社 2023-05-16 CN disclosed
US-20220380501-A1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION, AND CROSSLINKED RUBBER ZEON CORPORATION (JP) 2022-12-01 US disclosed
US-20220315684-A1 ACRYLIC RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2022-10-06 US disclosed
EP-3992218-A1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION, AND CROSSLINKED RUBBER Zeon Corporation (JP) 2022-05-04 EP disclosed
EP-3992236-A1 ACRYLIC RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2022-05-04 EP disclosed
CN-112768773-A Electrolyte and lithium ion battery 蜂巢能源科技有限公司 2021-05-07 CN disclosed
EP-3778661-A1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION, ACRYLIC RUBBER CROSSLINKED PRODUCT, SEAL MATERIAL, AND HOSE MATERIAL Zeon Corporation (JP) 2021-02-17 EP disclosed
US-20210009735-A1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION, CROSSLINKED ACRYLIC RUBBER, SEAL MATERIAL, AND HOSE MATERIAL ZEON CORPORATION (JP) 2021-01-14 US disclosed
CN-111918883-A Method for producing acrylic rubber, method for producing acrylic rubber composition, and biaxial extrusion dryer for acrylic rubber 日本瑞翁株式会社 2020-11-10 CN disclosed
WO-2019188709-A1 METHOD FOR PRODUCING ACRYLIC RUBBER, METHOD FOR PRODUCING ACRYLIC RUBBER COMPOSITION, AND TWIN-SCREW EXTRUSION DRYER FOR ACRYLIC RUBBERS 日本ゼオン株式会社 2019-10-03 WO disclosed
US-20110257361-A1 ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-10-20 US disclosed
US-4866095-A 1,8-dihydroxy-9-anthrones for treating warts or psoriasis GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIEQUES C.I.R.D. (FR) 1989-09-12 US disclosed
US-4558069-A TREATMENT OF SKIN DISORDERS GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1985-12-10 US disclosed
US-4465688-A FOR TREATMENT OF SKIN DISORDERS GROUPEMENT D'INTERET ECONOMIQUE CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1984-08-14 US disclosed
US-4464301-A FOR TREATMENT OF PSORIASIS GROUPEMENT D'INTERET ECONOMIQUE CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) 1984-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257361-A1 ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF PBRM1, PUF60, ALKBH1 EPHX1 3502/4885CA1 682/4885CA2 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.