SCHEMBL25320147

SCHEMBL25320147

O=C(O)C1C=C2NCCC2N1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7438175 0.62 SLC1A2 (0.37)
SCHEMBL18752480 0.58 ALDH1A1 (0.32)
SCHEMBL1004482 0.57 KDM4E (0.31)
SCHEMBL4413281 0.55 SMN1; SMN2 (0.37)
SCHEMBL28051654 0.55
SCHEMBL149411 0.55
SCHEMBL24108598 0.55
SCHEMBL16512417 0.54 EGLN1 (0.36) EGLN1
SCHEMBL28329183 0.54 EGLN1 (0.36) EGLN1
SCHEMBL2153717 0.52 GABRP (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023139085-A1 NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2023-07-27 WO disclosed