Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320354 | 1.00 | L3MBTL1 (0.43) | L3MBTL1PRKCIDYRK1ADYRK1BDYRK2 | |
| SCHEMBL25325872 | 0.89 | L3MBTL1 (0.43) | L3MBTL1PIK3CADRD2DRD3 | |
| SCHEMBL25325874 | 0.89 | L3MBTL1 (0.43) | L3MBTL1PIK3CADRD2DRD3 | |
| SCHEMBL24367134 | 0.78 | TDP1 (0.43) | L3MBTL1BRD4CREBBPMAOAMAOB | |
| SCHEMBL29081509 | 0.77 | ADRA2A (0.33) | L3MBTL1 | |
| SCHEMBL31145194 | 0.77 | ADRA2A (0.33) | L3MBTL1 | |
| SCHEMBL31145184 | 0.76 | L3MBTL1 (0.44) | L3MBTL1PIK3CAHDAC11 | |
| SCHEMBL31145226 | 0.76 | L3MBTL1 (0.44) | L3MBTL1PIK3CAHDAC11 | |
| SCHEMBL24363934 | 0.76 | L3MBTL1 (0.44) | L3MBTL1PIK3CAHDAC11 | |
| SCHEMBL10282948 | 0.72 | PRKCI (0.47) | PRKCIDYRK1ADYRK1BDYRK2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | RB1, CYP1B1, REN | L3MBTL1 4711/4885PRKCI 4183/4885DYRK1A 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.