Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2532048 | 1.00 | F2 (0.31) | F2F10PRSS1CCR2KDM1A | |
| SCHEMBL2532900 | 0.83 | CA1 (0.30) | — | |
| SCHEMBL2532898 | 0.83 | CA1 (0.30) | — | |
| SCHEMBL111131 | 0.82 | TEAD1 (0.34) | F2F10PRSS1CCR2KDM1A | |
| SCHEMBL3663155 | 0.81 | RXRB (0.46) | F2F10PRSS1CCR2 | |
| SCHEMBL3110578 | 0.81 | NLRP3 (0.39) | CCR2KDM1A | |
| SCHEMBL20492290 | 0.80 | GPR52 (0.46) | F2F10PRSS1CCR2 | |
| SCHEMBL1609341 | 0.77 | NPY5R (0.40) | KDM1A | |
| SCHEMBL3730602 | 0.77 | RXRA (0.35) | F2F10PRSS1CCR2 | |
| SCHEMBL1611211 | 0.76 | KDM1A (0.40) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633134-B2 | Substituted amidine compounds for combating animal pests | BASF SE (DE) | 2014-01-21 | — | — | US | disclosed |
| EP-2382195-A1 | SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-20110257011-A1 | Substituted Amidine Compounds for Combating Animal Pests | BASF SE (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2010072602-A1 | SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257011-A1 | Substituted Amidine Compounds for Combating Animal Pests | C5, C3AR1, C1S | F2 50/4885F10 563/4885PRSS1 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.