Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 8/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678698 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL29955992 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL29397237 | 0.82 | CYP3A4 (0.42) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL3966986 | 0.82 | CYP3A4 (0.42) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL30892256 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL659499 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL30892258 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL14577383 | 0.78 | ERN1 (0.46) | ALDH1A1CYP3A4MAPTPADI4ERN1 | |
| SCHEMBL841552 | 0.78 | CYP3A4 (0.48) | ALDH1A1CYP3A4MAPTPADI4ERN1 | |
| SCHEMBL909851 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109148-A1 | HETEROCYCLIC GLP-1 AGONISTS | SHANGHAI SHOUTI BIOTECHNOLOGY CO., LTD. (CN) | 2025-04-03 | — | — | US | disclosed |
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4469444-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023138684-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109148-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | ALDH1A1 1901/4885MEN1 450/4885KMT2A 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.